Interactions
The degron against the receptor: every peptide residue that comes within 4.5 angstrom of a receptor residue in the predicted ternary, coloured by closest approach. Hover a cell for the distance, click one to pin the pair and open it in the viewer. Only receptor residues that touch something are shown, because an axis of 1,184 residues of which fourteen are in contact is not a readable map.
PLIP answers a different question and is reported beside it: it is a protein-ligand tool, so it gives the glue's contacts with each protein and has nothing to say about where the degron meets the receptor, which is the interface Δ-ipTM is about.
Canonical fingerprint: CRBN
- HIS61 matched
- TRP63 matched
- TRP69 matched
- TRP83 matched
- PHE85 missing
Glue to degron
2 contact(s): ILE5, THR6
CONECT integrity
984 contiguous serials across atoms and TER records, 982 atoms, 19 CONECT records, all references resolvable